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Lupus Dermatosis (Exfoliative Cutaneous Lupus Erythematosus)

Lupus Dermatosis (Exfoliative Cutaneous Lupus Erythematosus)

March 03, 2019 by

Update February 23rd 2020

Recently PennGen has come up with a more accurate test for the Lupus Dermatosis, though still not 100 percent but I stress far more accurate! They retested all dogs and it did change some results of carrier to Clear / Non-Carrier, we experienced both dogs that tested as carrier to Healthy / Non Carriers. We have been testing all our dogs and very pleased that the testing has become more accurate. The stats in the original post have changed and fewer have tested as carriers which is great news. Eleanor and Luna's Pedigree in the first post, both tested clear with the new test.

Many dogs are being imported now, and there is a disease called Junctional Epidermolysis Bullosa (JEB) which can produce skin lesions and can be confused with Lupus Dermatosis with dogs being imported, it can also produce problems with footpads. There is a test for this in Europe, and anyone importing should be asking if dogs have been tested for this. 

Both are awful diseases that can be stopped, and I beleive testing for it is crucial to any breeding program, and that it should be part of any health guarantee! 

As breeders we often talk about genetics as far as pups ability, Drive, Conformation, Nose, Style, Tail Set and others, and breed for it, with all the tests available today for genetic health we as breeders should strive to produce not only talented dogs but healthy dogs even if we beileve them not to be in the line, testing just will give confirmation. I am the first to says not testing will likely produce healthy genetically sound dogs based on percentages, but lines can be protected to be healthy by testing. Most will say a carrier shouldn't be disqualified from a breeding program but testing can make it possible to be sure two carriers aren't bred I subscribe to this opinion.

Disclaimer, this is mine and only my opinion for the purpose of this post.

To start lets start with some statistics for LD in German Shorthaired Pointer's.

1699 GSP's tested 

1245 Tested Clear 72.3%

393 Tested Carriers 23.1%

61 Tested Affected. 3.6%

We have to keep in mind these are dogs Tested, I think we can safely say there a more carriers and affected in the GSP population than aren't reflected in these numbers!

On the onset I have received some criticism for becoming more vocal about this, but I own 2 GSP's both I purchased that tested as carriers, that constitutes a problem in my view! The two dogs I tested are both from Serbian Lines, but we know for sure this exists in American Bred Lines as well, I have also talked personally to two people who have affected dogs and learned from them how devastating this disease is not only on the dog but the families who love them unconditionally, so I won't apologize for becoming a strong advocate for testing!

I have been raising GSP's for 15 years and really just became aware of it less than 2 years ago, but having tested all my dogs now and having 2 be carrier's certainly caught my attention!

Eleanor

This first pedigree is Eleanor. I tested her and she came back as a carrier, so the breeder did the responsible thing tested both the sire and dam it revealed the Dam Kiss as the carrier, we know that as I tested Eto'o who I own and he was clear, which indicates Caput as the carrier so now you have to look at the Dam and Sire of Caput and so on to determine who are the carriers. It doesn't take long to see how this can spiral out of control if you can't pinpoint the problem.

Luna

The second dog is Luna I also purchased her, tested her and she is a carrier, I don't know if the Sire and Dam have been tested but if not certainly should be. to determine where in Luna's pedigree it is coming from! Both Luna and Eleanor are healthy carriers will never be affected, but if bred would pass it on to some of the pup's or worse if was bred to another carrier would have affected pups.

We need owner's who have dogs tested Clear, Carrier or affect post them, to help educate where the problems are. This disease like most Genetic can be prevented with testing. Put the same priority on testing for LD , Cones, DM, Von Willerbrand, as we do for Hip's Elbows, Eye's and Heart. If testing can prevent one dog from being affected and it will it's worth it!

If you are looking for a pup ask the breeder if they test for it, along with the other diseases!! In Many cases your going to pay 800.00 to $1,500.00 or more for a pup, small investment for a Breeder to make in their breeding stock!! As a puppy owner think of the peace of mind you will have knowing your pup is clear through parentage!

Testing is the only way to get a solid handle on what we are dealing with this disease, rather you think it doesn't run in the lines, or you suspect it may, or know for a fact it does, or not sure the more dogs tested the more accurate depiction that will be available. If you buy pups from a breeder who doesn't test for it, have your pup tested and do it right away, it is an inexpensive test to have done, that's the beauty of the test. I believe the more dogs tested the 23.1 percent carriers will go down, just my opinion. It is so important to get as many dogs that test clear in these numbers as it is carriers and Affected. This particular disease is specific to the GSP breed. 

Penngen is the only Laboratory that does this test!!! Website

I can't think of a reason not to test when a test is available!

Posted in: Vom Sage Brush News

Reader Comments

2 Comments on Lupus Dermatosis (Exfoliative Cutaneous Lupus Erythematosus)

Thanks for posting this information. I wish I had known about this disease before I had gotten my GSP who is an affect. I love her and doing everything I can for her to have a good life.

Denise Yabi March 5, 2019 12:03 PM

I appreciate your dilegence to keeping the breed healthy. Thank you for your commitment to the breed. Since my family’s involvement with the breed goes back to my great grandfather (I’m in my mid 60’s) brought his GSP from Austria to Montana, and I grew up with GSPs and have probably my last one, I have known and appreciated your passion for the breed. Thank you

Missy Newcom March 8, 2019 12:03 PM

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